Chemistry
Preparation of 3-quinuclidone (c.f. quinuclidine) has been documented.
The last step of the procedure appears to be a Dieckmann cyclization (intramolecular Claisen condensation) followed by decarboxylation.
Additionally, benzilic acid is made in a few steps starting from benzaldehyde and cyanide catalyst.
3-Quinuclidone is a drug precursor for medicinal (neuroprotective) as well as military applications, c.f. PNU-282,987.
Read more about this topic: 3-Quinuclidinyl Benzilate
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“If thought makes free, so does the moral sentiment. The mixtures of spiritual chemistry refuse to be analyzed.”
—Ralph Waldo Emerson (1803–1882)
“For me chemistry represented an indefinite cloud of future potentialities which enveloped my life to come in black volutes torn by fiery flashes, like those which had hidden Mount Sinai. Like Moses, from that cloud I expected my law, the principle of order in me, around me, and in the world.... I would watch the buds swell in spring, the mica glint in the granite, my own hands, and I would say to myself: “I will understand this, too, I will understand everything.””
—Primo Levi (1919–1987)
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—Ellen Henrietta Swallow Richards (1842–1911)