5-alpha Reductase
5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism. They participate in 3 metabolic pathways: bile acid biosynthesis, androgen and estrogen metabolism, and prostate cancer.
5α-reductases catalyze the following chemical reaction:
- a 3-oxo-5α-steroid + acceptor a 3-oxo-Delta4-steroid + reduced acceptor
Thus, the two substrates of these enzymes are a 3-oxo-5α-steroid and acceptor, whereas its two products are 3-oxo-Delta4-steroid and a reduced acceptor.
Read more about 5-alpha Reductase: Function, Isoenzymes, Production and Inhibition, Pharmacology, Nomenclature
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