Receptor Types
Molecular biology has shown that the nicotinic and muscarinic receptors belong to distinct protein superfamilies.
Drug | Nm | Nn | M1 | M2 | M3 |
---|---|---|---|---|---|
ACh, Charbacol, AChEi (Psysostigmine, Galantamine, Neostigmine, Pyridostigmine) | + | + | + | + | + |
Nicotine, Varenicline | + | + | |||
Succinylcholine | +/- | ||||
Atracurium, Vecuronium, Tubocurarine, Pancuronium | - | ||||
Epibatidine, DMPP | + | ||||
Trimethaphan, Mecamylamine, Bupropion, Dextromethophan, Hexamethonium | - | ||||
Muscarine, Methacholine, Oxotremorine, Bethanechol, Pilocarpine | + | + | + | ||
Atropine, Tolterodine, Oxybutynin | - | - | - | ||
Vedaclidine, Talsaclidine, Xanomeline, Ipatropium | + | ||||
Pirenzepine, Telenzepine | - | ||||
Methoctramin | - | ||||
Darifenacin, 4-DAMP, Darifenacin, Solifenacin | - |
Read more about this topic: Acetylcholine Receptor
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