Activator may mean:
- Activator (genetics), a DNA-binding protein that regulates one or more genes by increasing the rate of transcription
- Activator (proteomics), a type of effector that increases the rate of enzyme mediated reactions
- Activator (phosphor), a type of dopant used in phosphors and scintillators
- Sega Activator, a motion-sensing controller for the Sega Mega Drive/Genesis
- Activator technique, a method of spinal adjustment
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