Appleseed may refer to:
- The seed of an apple
- Johnny Appleseed, an American pioneer nurseryman and missionary
- Appleseed (EP), by Aesop Rock
- Appleseed Recordings, a record label
- Appleseed Foundation, a non-profit network of social justice centers
- Project Appleseed, a rifle marksmanship and historical awareness program
- Appleseed, a novel by John Clute
Read more about Appleseed: Manga and Spin-offs
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