ASIS may refer to:
- Alam Shah Science School, a prestigious fully residential school in Malaysia
- Australian Secret Intelligence Service
- Ada Semantic Interface Specification (ISO/IEC 15291)
- American Society for Information Science and Technology, sometimes known as the American Society for Information Science (ASIS)
- ASIS International, a professional organisation focused on the security industry, formerly American Society for Industrial Security
- Anterior superior iliac spine
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