Barb may refer to:
- A backward-facing point on a fish hook or similar implement, rendering extraction from the victim's flesh more difficult
- Wind barbs for each station on a map of reported weather conditions
- Barb (feather), the branches issuing from the rachis of feathers
- Barb (fish), several species of freshwater fish
- Barb (horse), a breed from North Africa
- Barb (pigeon), a breed of domestic pigeon
- BARB, the Broadcasters' Audience Research Board
- Barb, a shortened version of Barbara (given name)
- Barding or barb, a type of armor for horses
- Australian Kelpie or barb, a breed of dog
- A type of pipe fitting called barb, used to connect hosing (the ridges face backward, making insertion easy and removal difficult)
- Barb, a shortened version of barbiturate, a drug that acts as a depressant for the central nervous system
- USS Barb, the name of two submarines of the US Navy
- Barb, a term used by Nicki Minaj's fans to refer to themselves
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