Brunelleschi may refer to:
- Filippo Brunelleschi (1377 - 1446), one of the foremost architects and engineers of the Italian Renaissance
- Brunelleschi's Dome
- 6055 Brunelleschi (2158 T-3), a Main-belt Asteroid discovered in 1977
- Umberto Brunelleschi (born 1879, Montemurdo - 1949), an Italian artist
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