CBU may refer to:
- Universities
- California Baptist University, in Riverside, California
- Christian Brothers University, in Memphis, Tennessee
- Cape Breton University, in Sydney, Nova Scotia
- Celal Bayar University, in Manisa, Turkey
- Copperbelt University, in the Copperbelt region of Zambia
- Chungbuk National University, in Cheongju, South Korea
- Radio stations
- CBU (AM), a radio station (690 AM) licensed to Vancouver, British Columbia, Canada
- CBU-FM, a radio station (105.7 FM) licensed to Vancouver, British Columbia, Canada
- Computing
- Capacity Back Up, an IBM term for a range of optional commercial offerings (CBU example) which provide additional capacity on demand for some of the mainframe and server models in the IBM range. Customers are given the facility to access additional backup processor capacity to deal with unplanned situations in which customers have lost capacity or in which their capacity usage has unexpectedly exceeded the maximum available from their installed kit.
- Other
- Cellular Backhaul Unit used in FTTx deployments.
- Cluster bombs
- Cluster box unit, a mailbox with multiple receptacles
- Cognition and Brain Sciences Unit, a branch of the UK Medical Research Council
- The stock ticker for Community Bank System, Inc.
- Complete Build-up Unit or Completely Built Unit, manufactured goods for export in completely built form, also known as BUX (Built up export) form
- The IATA airport code for Cottbus-Drewitz Airport
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