Centro (Italian, Portuguese and Spanish for center, also downtown) may refer to:
Places:
- Centro Region, one of the regions of Portugal
- Centro (municipality), a municipality in the Mexican state of Tabasco
- Centro (Niterói), a neighborhood of Niterói in Brazil
- Centro, Porto Alegre, a neighborhood of Porto Alegre in Brazil
- Centro (Rio de Janeiro), (the downtown) neighborhood of Rio de Janeiro in Brazil
- Centro Habana, Cuba
- Centro (Mexico City), Mexico
- Centro, Mandaue City, a barrio in The Philippines
- Centro (Madrid), Spain
- Centro, Montevideo, downtown barrio of Montevideo, Uruguay
Companies:
- Centro Properties Group, a retail property developer, owner and manager in Australia, United States of America and New Zealand
- Centro (company), a company headquartered in Chicago, Illinois, USA
Cultural:
- Centro Asturiano de México
- Centro Cultural Bella Época, Mexico
- Centro Cultural de la Raza, a cultural center in San Diego, California, USA
- Museo Nacional Centro de Arte Reina Sofía, Spain
- Luis A. Ferré Performing Arts Center, Puerto Rico
- El Centro Cultural de Mexico, a community space in Santa Ana, Orange County, California, USA
- El Centro de la Raza, a cultural center in Seattle, Washington, USA
Transport:
- Centro, the Central New York Regional Transportation Authority in the United States
- Centro, the West Midlands Passenger Transport Executive in the United Kingdom
- Plaxton Centro, a bus body built by Plaxton in the UK
Shopping:
- Centro Properties Group, a retail property developer, owned and managed in Australia, United States of America and New Zealand
- CentrO, a shopping mall in Oberhausen, Germany
Media:
- CENTRO Tampa, a Spanish-language newspaper in Tampa, Florida, USA
Products:
- Palm Centro