Charles Emmanuel may refer to:
- Charles Emmanuel de Savoie, 3rd Duc de Nemours, (1567–1595)
- Charles Emmanuel I, Duke of Savoy (1562–1630)
- Charles Emmanuel II, Duke of Savoy (1634–1675)
- Charles Emmanuel III of Sardinia (1701–1773)
- Charles McArthur Emmanuel, U.S. citizen and the son of Charles Taylor, former President of Liberia.