CKD may refer to:
- Chronic kidney disease, a slowly progressive loss of renal function
- Complete knock down, a complete kit needed to assemble a vehicle
- Count Key Data, a disk architecture used in IBM mainframe computers
- ČKD (Českomoravská Kolben-Daněk), an engineering company in the Czech Republic
- Crooked Creek Airport in Alaska, United States (IATA airport code)
- Cyclic ketogenic diet, a low carbohydrate diet with intermittent periods of high carbohydrate consumption
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