COPA may stand for:
- Choice of Plausible Alternatives, a natural language processing task to select the alternative that is more plausibly the cause (or effect) of the situation described by the premise
- Child Online Protection Act, a former U.S. law to protect minors from certain material on the internet
- Not to be confused with the Children's Internet Protection Act (CIPA), the Children's Online Privacy Protection Act (COPPA) or COPA's predecessor legislation, the Communications Decency Act (CDA)
- Canadian Owners and Pilots Association
- Cirrus Owners and Pilots Association, an aircraft type club
- Parliamentary Conference of the Americas
- COPA (gene), a human gene that encodes the coatomer subunit alpha protecin
- Control of Pollution Act, 1974
- COntrolling Profitability Analysis, Profitability Analysis (SAP)
- Canadian Office Products Association
- Coalition On Political Assassinations
- Cancer Outlier Profile Analysis
Copa may refer to:
- Copa Airlines, an international airline based in Panama
- Copa America, the main association football competition of the South American men's national football teams
- Copa (genus), a genus of spiders in the Corinnidae family
- Copolyamide, a type of thermoplastic elastomer
- Copacabana (nightclub), a nightclub in New York City
- Copa (dance move), a standard move in Salsa and Mambo dancing (named after the Copacabana (nightclub))
- CoPa, a short-lived nickname for Comerica Park in Detroit
- Boubacar Barry, Ivorian footballer
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