The acronym CUF may mean:
- Centre Party Youth, Centerpartiets Ungdomsförbund, the youth organization of the Center Party in Sweden
- Center for Union Facts, an advocacy group critical of unions
- Civic United Front, a political party in Tanzania
- Companhia União Fabril, a Portuguese company
- Grupo Desportivo Fabril do Barreiro, formerly the Grupo Desportivo da Companhia União Fabril, a Portuguese football (soccer) team
- Clifton Heights, University Heights, and Fairview, a neighborhood in Cincinnati, Ohio
- Common Update Framework, an open source project designed to unify the process of updating applications
- The IATA airport code for Cuneo Levaldigi Airport, Piedmont, Italy