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- Candida Doyle (born 1963), Irish musician
- Cartha Doyle (born 1929), All-American Girls Professional Baseball League player
- Charles Altamont Doyle (1832–1893), Victorian artist
- Charles Hastings Doyle (1804–1883), British military officer
- Chris Doyle, American multi-media artist
- Christopher Doyle (born 1952), Australian cinematographer
- Clyde Doyle (1887–1963), U.S. Representative from California
- Colin Doyle (born 1977), Canadian lacrosse player
- Colin Doyle (born 1985), Irish footballer
- Craig Doyle (born 1970), Irish television and radio presenter
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