Dysgenesis may refer to:
- Dysgenesis (embryology), which indicates abnormal organ development during embryonic growth and development
- Anterior segment dysgenesis, a failure of the normal development of the tissues of the anterior segment of the eye
- "Hybrid dysgenesis", which relates to a high mutation rate in certain Drosophila strains caused by the transposition of P elements
- The study of dysgenics, a theory that deterioration of hereditary qualities can occur in offspring due to survival of or reproduction by less well-adapted individuals