Encephalopathy - Types

Types

There are many types of encephalopathy. Some examples include:

  • Mitochondrial encephalopathy—Metabolic disorder caused by dysfunction of mitochondrial DNA. Can affect many body systems, particularly the brain and nervous system.
  • Glycine encephalopathy—A genetic metabolic disorder involving excess production of glycine
  • Hepatic encephalopathy—Arising from advanced cirrhosis of the liver
  • Hypoxic ischemic encephalopathy—Permanent or transitory encephalopathy arising from severely reduced oxygen delivery to the brain
  • Static encephalopathy—Unchanging, or permanent, brain damage
  • Uremic encephalopathy—Arising from high levels of toxins normally cleared by the kidneys—rare where dialysis is readily available
  • Wernicke's encephalopathy—Arising from thiamine deficiency, usually in the setting of alcoholism
  • Hashimoto's encephalopathy—Arising from an auto-immune disorder
  • Hypertensive encephalopathy—Arising from acutely increased blood pressure
  • Chronic traumatic encephalopathy—Progressive degenerative disease associated with multiple concussions and other forms of head injury
  • Lyme encephalopathy—Arising from Lyme disease bacteria, including Borrelia burgdorferi.
  • Toxic encephalopathy—A form of encephalopathy caused by chemicals, often resulting in permanent brain damage
  • Toxic-Metabolic encephalopathy—A catch-all for brain dysfunction caused by infection, organ failure, or intoxication
  • Transmissible spongiform encephalopathy—A collection of diseases all caused by prions, and characterized by "spongy" brain tissue (riddled with holes), impaired locomotion or coordination, and a 100% mortality rate. Includes bovine spongiform encephalopathy (mad cow disease), scrapie, and kuru among others.
  • Neonatal encephalopathy—an obstetric form, often occurring due to lack of oxygen in bloodflow to brain-tissue of the fetus during labour or delivery
  • Salmonella encephalopathy —A form of encephalopathy caused by food poisoning (especially out of peanuts and rotten meat) often resulting in permanent brain damage and nervous system disorders.
  • Encephalomyopathy, a combination of encephalopathy and myopathy. Causes may include mitochondrial disease (particularly MELAS) or chronic hypophosphatemia, as may occur in cystinosis.

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