As An Abbreviation
- Ecole Supérieure de Commerce, a business school in the French system of "Grandes Ecoles"
- Eddy Street Commons
- Eden Synthetic Corps, a band from Portugal known for their harsh aggrotech music.
- Edison State College
- Edmonton Ski Club
- Electronic stability control
- Electronic Systems Center
- Electronic Speed Control
- Embedded Systems Conference
- Embryonic stem cell
- Empire State College
- Empire Supporters Club
- English Silver Coinage by P. Alan Rayner
- English Subject Centre
- Environmental Stress Cracking, one of the most common causes of unexpected brittle failure of thermoplastic polymers
- Equitable Stroke Control, a feature of golf handicapping
- Escanaba, Michigan, the International Air Transport Association code for Delta County Airport
- Essential Services Commission (disambiguation), several meanings
- Essex Senior Cup, a football competition in Essex, England
- Essex Skating Club
- Eurobodalla Shire Council
- European Shooting Confederation
- European Social Charter
- European Society of Cardiology
- European Students Conference, the largest biomedical scientific conference in Europe entirely run by students
- Eurovision Song Contest
- Sustainment Command (Expeditionary)
- European Space Camp
- European Super Cup
- Extended static checking
- External secret agencies, Ukrainian intelligence agency
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