GK or Gk may mean or refer to:
- Gk., an abbreviation for Greek, especially Greek language
- General knowledge
- GK Reid, an American fashion stylist and TV star of Bravo's Double Exposure
- Gabriel Knight, a series of adventure games
- Gallien-Krueger, an instrument amplifier company
- Gameknot, an online chess-playing website
- Garrison Keillor, an American radio show host
- Gawad Kalinga, an anti-poverty movement based in the Philippines
- Genghis Khan emperor of Asia
- Gigakelvin, an SI unit of temperature
- Gōdō gaisha, a type of Japanese business organization known as GK
- Goalkeeper, in sports short-hand
- Godskitchen, an international superclub and trance music brand
- Greater Kailash, New Delhi, India
- Guernsey, FIPS PUB 10-4 territory code
- Geilenkirchen, a German city
- Graham-Kapowsin High School in Pierce County, Washington
- GateKeeper (roller coaster), a Wing Coaster at Cedar Point amusement park
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