The term HRO can refer to:
- Harold Wood railway station, a railway station in London, England having National Rail station code HRO.
- The Harvard Radcliffe Orchestra, a collegiate symphony orchestra in Cambridge, Massachusetts.
- High reliability organization, an organization that has succeeded in avoiding catastrophes in an environment where normal accidents can be expected due to risk factors and complexity.
- Holme Roberts & Owen, a Colorado-based law firm.
- National HRO, a communications receiver manufactured by the National Radio Company.
- Boone County Airport (Arkansas), an airport in Harrison, Arkansas having IATA code HRO.
- Harassment Restraining Order, a type of restraining order.