Hypoxia may refer to:
- Hypoxia (environmental), reduced dissolved oxygen content of a body of water detrimental to aerobic organisms
- Hypoxia in fish, responses of fishes to hypoxia
- Hypoxia (medical), a pathological condition in which the body or a region of the body is deprived of an adequate oxygen supply
- Autoerotic hypoxia or erotic asphyxiation, intentional restriction of oxygen to the brain for sexual arousal
- Cerebral hypoxia or cerebral anoxia, a reduced supply of oxygen to the brain
- Diffusion hypoxia or Fink effect, a factor that influences the partial pressure of oxygen within the pulmonary alveolus
- Histotoxic hypoxia, the inability of cells to take up or utilize oxygen from the bloodstream
- Hypoxemic hypoxia or hypoxemia, a deficiency of oxygen in arterial blood
- Hypoxia drive, a respiratory drive in which the body uses oxygen chemoreceptors to regulate the respiratory cycle
- Hypoxic hypoxia, a result of insufficient oxygen available to the lungs
- Intrauterine hypoxia, when a fetus is deprived of an adequate supply of oxygen
- Latent hypoxia or deep water blackout, loss of consciousness on ascending from a deep freedive
- Tumor hypoxia, the situation where tumor cells have been deprived of oxygen
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