Computers
- Image Cytometry Standard, a digital multidimensional image file format used in life sciences microscopy
- Information and Computer Science, the combined field of informatics and computing
- Internet chess server, an external server that provides the facility to play, discuss, and view chess over the Internet
- Internet Connection Sharing, a feature in Microsoft operating systems since the advent of Windows 98 Second Edition
- .ics, a filename extension for iCalendar files
- Ice Cream Sandwich (operating system), the codename for version 4.0 of the Android operating system
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