Illini can refer to:
- Chief Illiniwek, formerly the mascot of the University of Illinois at Urbana-Champaign
- Illiniwek, a group of six Native American tribes in the upper Mississippi River valley of North America
- Illinois Fighting Illini, the intercollegiate sports teams of the University of Illinois at Urbana-Champaign
- Illini (Amtrak), a passenger train operated by Amtrak
- Illini State Park, an Illinois State Park on the Illinois River