Signs and Symptoms
These depend on poorly understood variations in individual biology and consequently may not be found with all people diagnosed with insulin resistance.
- Fatigue.
- Brain fogginess and inability to focus.
- High blood sugar.
- Intestinal bloating – most intestinal gas is produced from carbohydrates in the diet, mostly those that humans cannot digest and absorb.
- Sleepiness, especially after meals.
- Weight gain, fat storage, difficulty losing weight – for most people, excess weight is from high fat storage; the fat in IR is generally stored in and around abdominal organs in both males and females. It is currently suspected that hormones produced in that fat are a precipitating cause of insulin resistance.
- Increased blood triglyceride levels.
- Increased blood pressure. Many people with hypertension are either diabetic or pre-diabetic and have elevated insulin levels due to insulin resistance. One of insulin's effects is to control arterial wall tension throughout the body.
- Increased pro-inflammatory cytokines associated with cardiovascular disease.
- Depression. Due to the deranged metabolism resulting from insulin resistance, psychological effects, including depression, are not uncommon.
- Acanthosis nigricans.
- Increased hunger.
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