Intestine - Diseases and Disorders

Diseases and Disorders

• Gastroenteritis is an inflammation of the intestines. It is the most common disease of all the intestines.
• Ileus is a blockage of the intestines.
• Ileitis is an inflammation of the ileum.
• Colitis is an inflammation of the large intestine.
• Appendicitis is inflammation of the vermiform appendix located at the caecum. This is a potentially fatal disease if left untreated; most cases of appendicitis require surgical intervention.
• Coeliac disease is a common form of malabsorption, affecting up to 1% of people of northern European descent. An autoimmune response is triggered in intestinal cells by digestion of gluten proteins. Ingestion of proteins found in wheat, barley and rye, causes villous atrophy in the small intestine. Lifelong dietary avoidance of these foodstuffs in a gluten-free diet is the only treatment.
• Crohn's disease and ulcerative colitis are examples of inflammatory bowel disease. While Crohn's can affect the entire gastrointestinal tract, ulcerative colitis is limited to the large intestine. Crohn's disease is widely regarded as an autoimmune disease. Although ulcerative colitis is often treated as though it were an autoimmune disease, there is no consensus that it actually is such. (See List of autoimmune diseases).
• Enteroviruses are named by their transmission-route through the intestine (enteric meaning intestinal), but their symptoms aren't mainly associated with the intestine.
• Irritable bowel syndrome (IBS) is the most common functional disorder of the intestine. Functional constipation and chronic functional abdominal pain are other disorders of the intestine that have physiological causes, but do not have identifiable structural, chemical, or infectious pathologies. They are aberrations of normal bowel function but not diseases.
• Diverticular disease is a condition that is very common in older people in industrialized countries. It usually affects the large intestine but has been known to affect the small intestine as well. Diverticulosis occurs when pouches form on the intestinal wall. Once the pouches become inflamed it is known as diverticulitis.
• Endometriosis can affect the intestines, with similar symptoms to IBS.
• Bowel twist (or similarly, bowel strangulation) is a comparatively rare event (usually developing sometime after major bowel surgery). It is, however, hard to diagnose correctly, and if left uncorrected can lead to bowel infarction and death. (The singer Maurice Gibb is understood to have died from this.)
• Angiodysplasia of the colon
• Chronic functional abdominal pain
• Colorectal cancer
• Constipation
• Diarrhea
• Hirschsprung's disease (aganglionosis)
• Intussusception
• Polyp (medicine) (see also Colorectal polyp)
• Pseudomembranous colitis
• Ulcerative colitis and toxic megacolon