Jak may refer to:
- JAK, Jazakomu Allahu Khayran (a way of thanking in Islam)
- JAK members bank, a Swedish interest-free bank
- Janus kinase, an intracellular signaling molecule; component of the JAK-STAT signal system
- Jak (Jak and Daxter), the main character of the Jak and Daxter video game series
- Jak (comics), a comic strip in the UK comic book The Dandy
- Alternative spelling of the male name Jack
- Ják, a village in Hungary
- Raymond Jackson ("JAK") (1927–1997), cartoonist of the London Evening Standard
- Jan Amos Komenský (Comenius), Czech theologian, educator and writer; the last bishop of Unity of the Brethren
- Janus kinase 1, a protein
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