JC

JC may refer to:

• Slang reference to Jesus Christ
• "JC" (song), a 1996 song by Powderfinger
• JC virus, a type of human polyomavirus
• The Jewish Chronicle, a national British Jewish newspaper
• Junior college, a type of two-year school of higher education
• Jamaica College, a boys' high school in Kingston, Jamaica
• Jamestown College, a private liberal arts college in Jamestown, North Dakota
• Jones College (Jacksonville), a private college in Jacksonville, Florida
• Jeassy, Indian film director and actor
• JC, an emblem of a clothing line by Jackie Chan