KRS is an abbreviation that can mean:
- KRS-One (born 1965), one of several pseudonyms for Lawrence Krisna Parker, an American hip-hop musician
- Kill Rock Stars, an American record label
- "Knowledge representation system" (see Knowledge representation), a system for library classification and for processing concepts in an information system
- "Knowledge retrieval system" (see Information retrieval), an information retrieval system which includes aspects of knowledge retrieval
- Krishna Raja Sagara (India), name of both a lake and the dam that causes it
- Kristiansand Airport, Kjevik, IATA airport code
- KRS Film Distributors (Malta)
- Kamen Rider Stronger, a Japanese television series
- Kuju Rail Simulator, a train simulator in development by Kuju Entertainment
- Kadet Remaja Sekolah, a government youth organisation in Malaysia
- Kentucky Revised Statutes, the statutory law of the U.S. state of Kentucky