Ladysmith is the name of several places:
- Ladysmith, British Columbia, Canada
- Ladysmith, Wisconsin, United States
- Ladysmith, KwaZulu-Natal, South Africa
- Ladysmith, New South Wales, Australia
- Ladysmith, Virginia, United States
- Ladysmith Island, Queensland, Australia, an island in the Smith Islands National Park, a group that includes Blacksmith, Goldsmith, and Ladysmith Islands, among others
Ladysmith can also refer to:
- Ladysmith (novel) (1999) is Giles Foden’s second novel
- Ladysmith Black Mambazo, a South African choral group
- Siege of Ladysmith, 1900
- Smith & Wesson Ladysmith, a small handgun