Lair may refer to:
- Animal lair, a shelter built or used by an animal
- Lair (video game), a 2007 video game
- Burial plot in a graveyard, in Scots language
- Demon's Lair, fantasy role-playing game system created in 1997 by Lasalion Games
- Devil's Lair, a large cave in Australia
- Dragon's Lair, a laserdisc video game
- Irma Lair, fictional character in the comic book W.I.T.C.H. and the animated series of the same name
- Mike Lair (born 1946), American politician
- Seduction lair or mens lair is a mens social club and study group centered around courtship initiation and development
- Tiger's Lair, official football student section for the University of Missouri
- Wolf's Lair, Adolf Hitler's first Eastern Front military headquarters
- The Lair, 2007-8 American gay-themed vampire television series
- The Lair, nickname for the location in the "Valley of the Gods" where Stringfellow Hawke kept the helicopter Airwolf hidden in the 1980s TV action-adventure series Airwolf