Animals
Many animals use the variation in duration of melatonin production each day as a seasonal clock. In animals including humans the profile of melatonin synthesis and secretion is affected by the variable duration of night in summer as compared to winter. The change in duration of secretion thus serves as a biological signal for the organisation of daylength-dependent (photoperiodic) seasonal functions such as reproduction, behaviour, coat growth and camouflage colouring in seasonal animals. In seasonal breeders that do not have long gestation periods and that mate during longer daylight hours, the melatonin signal controls the seasonal variation in their sexual physiology, and similar physiological effects can be induced by exogenous melatonin in animals including mynah birds and hamsters.
In mammals, melatonin is biosynthesized in four enzymatic steps from the essential dietary amino acid tryptophan, with serotonin produced at the second step. Melatonin is secreted into the blood by the pineal gland in the brain. Known as the "hormone of darkness," it is secreted in darkness in both day-active (diurnal) and night-active (nocturnal) animals. It may also be produced by a variety of peripheral cells such as bone marrow cells, lymphocytes, and epithelial cells. Usually, the melatonin concentration in these cells is much higher than that found in the blood, but it does not seem to be regulated by the photoperiod.
Read more about this topic: Melatonin
Famous quotes containing the word animals:
“To err is human also in so far as animals seldom or never err, or at least only the cleverest of them do so.”
—G.C. (Georg Christoph)
“There is nothing worse than an idle hour, with no occupation offering. People who have many such hours are simply animals waiting docilely for death. We all come to that state soon or late. It is the curse of senility.”
—H.L. (Henry Lewis)
“The greatness of man is so evident that it is even proved by his wretchedness. For what in animals is nature, we call in man wretchedness—by which we recognize that, his nature being now like that of animals, he has fallen from a better nature which once was his.”
—Blaise Pascal (1623–1662)