Development
During embryonic development, the midbrain arises from the second vesicle, also known as the mesencephalon, of the neural tube. Unlike the other two vesicles, the prosencephalon and rhombencephalon, the mesencephalon remains undivided for the remainder of neural development. It does not split into other brain areas. while the prosencephalon, for example, divides into the telencephalon and the diencephalon.
Throughout embryonic development, the cells within the midbrain continually multiply and compress the still-forming Aqueduct of Sylvius or cerebral aqueduct. Partial or total obstruction of the cerebral aqueduct during development can lead to congenital hydrocephalus.
Read more about this topic: Midbrain
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