MIPS may refer to:
- Maharana Institute of Professional Studies, an institution in Kanpur, Uttar Pradesh, India
- Mansehra International Public School and College, in Mansehra, Pakistan
- Material input per unit of service, an economic efficiency indicator
- Menards Infiniti Pro Series, a former name of an Indy Pro Series automobile race
- Millon Index of Personality Styles, a psychological assessment tool providing information on psychopathology
- Monthly income preferred stock, a financial instrument
- Multiband Imaging Photometer for Spitzer, an instrument on the Spitzer Space Telescope
- Munich Information Center for Protein Sequences, a genomics research center in Germany
In computing:
- Million instructions per second, a measure of a computer's central processing unit performance
- MIPS architecture, a RISC instruction set architecture
- MIPS Technologies, formerly MIPS Computer Systems, developer of the MIPS architecture
- Maximum intensity projection, a volume rendering technique
- A golden rabbit found in Super Mario 64.