Molon ( /ˈmoʊlən/ or /ˈmoʊˌlɒn/) or Molo ( /ˈmoʊloʊ/; Ancient Greek: Moλων; died 220 BC) was a general and satrap of the Seleucid king Antiochus the Great (223–187 BC). He held the satrapy of Media at the accession of that monarch (223 BC); in addition to which, Antiochus conferred upon him and his brother Alexander the government of all the upper provinces of his empire. But their hatred to Hermeias, the chief minister of Antiochus, soon led them both to revolt: the two generals at first sent against them by the king were unable to oppose their progress, and Molon found himself at the head of a large army, and master of the whole country to the east of the Tigris.
He was, however, foiled in his attempts to pass that river by Zeuxis. However, Xenoetas, the general of Antiochus, who was now sent against him with a large force, having ventured to cross it in his turn, was surprised by Molon, and his whole army cut to pieces. The rebel satrap now crossed the Tigris, and made himself master of the city of Seleucia on the Tigris together with the whole of Babylonia and Mesopotamia.
The formidable character of the insurrection had persuaded, at length, Antiochus to march in person against the rebels. After wintering at Nisibis, he crossed the Tigris, 220 BC, and advanced southwards against Molon, who marched from Babylon to meet him. A pitched battle ensued, in which the desertion of the left wing of the rebel army at once decided the victory in favour of the king. Molon himself put an end to his own life, to avoid falling into the hands of the enemy: but his body was crucified by order of Antiochus, or rather of his minister Hermeias.