Morpheus may refer to:
- Characters
- Morpheus (mythology), the principal god of dreams in the Greek mythology
- Morpheus (DC comics), a moniker for Dream, a fictional god of dreams in the comic book The Sandman
- Morpheus (The Matrix), a character of The Matrix franchise
- King Morpheus, a fictional character in the Little Nemo comics
- Morpheus (Deus Ex), a minor artificial intelligence character in the game Deus Ex
- Morpheus (Percy Jackson) a minor character who appears in the last book in the series and is the god of dreams.
- Morpheus D. Duvall, the principal antagonist of Resident Evil: Dead Aim.
- Technology
- Morpheus (computer program), file-sharing client/server software operated by the company StreamCast
- Morpheus (morphing software) is a morphing software for Windows and Mac OS X
- Morpheus (1987 video game), a video game developed by Andrew Braybrook in 1987
- Morpheus (1998 video game), a video game released in 1998
- Morpheus lemmatiser, Greek and Latin morphological parser and lemmatising software produced by Perseus Project
- Project Morpheus, NASA project to produce a vertical test bed and pre-prototype lunar lander called Morpheus
- Music
- Morpheus, a composition for viola and piano by Rebecca Helferich Clarke
- Morpheus (album), a music album by Canadian group Delerium
- Morpheus (musician), a Spanish dark ambient and industrial ambient artist
- Morpheus (band) an American death metal band formed in 1990,changed name to Morpheus Descends in 1992
- Morpheus (band) an American thrash metal band formed in 1992
- Morpheus (Synthesizer) produced in the mid-1990s by E-mu Systems
- Other
- "Morpheus" (Stargate SG-1), an episode of the sci-fi TV series Stargate SG-1