NEM may refer to:
- New Economic Model, an ongoing initiative to reform Malaysia's economy
- Nem or Nem rán, a variant term for the Vietnamese dish Chả giò
- Le Nouvel Ensemble Moderne, a chamber orchestra from Montreal specializing in contemporary classical music
- National Electricity Market, Australian interstate electricity distribution grid
- National Equality March, a 2009 LGBT rights protest in Washington, D.C.
- N-Ethylmaleimide, a biochemical tool
- Networked and Electronic Media, a European industrial initiative
- New Economic Mechanism, economic reforms undertaken in Hungary in 1968 and in Laos in 1986
- Newmont Mining, a corporation with New York Stock Exchange symbol NEM
- Normen Europäischer Modellbahnen, the European standards for model railroads issued by the MOROP
- "Nothing Else Matters", a song on the 1991 self-titled album by Metallica
- Nottingham East Midlands Airport, the former name of East Midlands Airport in the United Kingdom.
- Net energy metering, a program offered by utilities in various districts to incentivize renewable energy
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