OS may refer to:
- O.S. Old Stonyhurst, an old boy of the ancient Jesuit public school, Stonyhurst College
- O.S. Engines, a Japanese manufacturer of model aircraft engines
- Ocean Science, an Oceanographic Journal published by the European Geosciences Union.
- Oculus sinister, meaning "left eye" in eyeglass prescriptions
- "Old Style date" (as "O.S."), a date designation indicating derivation from the Julian Calendar, as opposed to "N.S." indicating derivation from the Gregorian Calendar (see Old Style and New Style dates)
- Open SEAT, a tennis tournament in Barcelona now known as the Torneo Godó
- Open source, a software development model
- Operating system, a software that manages the hardware and software of a computer
- Order of Santiago, Spanish order dedicated to St James the Greater
- Ordinary Seaman (occupation), an unlicensed member of the deck department of a merchant ship
- Ordnance Survey, the national mapping agency for Great Britain
- Ohtahara syndrome, a brain disorder
- Opening snap, a heart sound present in individuals with AV valve stenosis
- Outlaw Star, a manga and anime series
- Austrian Airlines (IATA designator)
- Ossetic language (ISO 639-1 abbreviation)
- Ordnance Sergeant
- Overall Survival
- On-Sight Climbing, the ascent of a rock climbing route on the first attempt, with no falls, without prior knowledge of its specifics beyond its difficulty rating and number of protection points, if a bolted climbing route. An "On-Sight" climb refers to the manner of ascent, and is considered the best style attainable.
os may refer to:
- os, a mouth or external opening (from the Latin), also ostium. In particular:
- external os, the external orifice of the uterus
- internal os, the internal orifice of the uterus
- os or ostium, the "mouth" of a coronary artery
Os may refer to:
- Os, Hedmark, a municipality in Norway
- Os, Hordaland, a municipality in Norway
- Os, Østfold, a parish in Norway
- Ōs, in Old English denoting a god in Anglo-Saxon paganism
- Osmium, a chemical element whose symbol is "Os"
- Os du Randt (born 1972), South African rugby player
- Os Guinness (born 1941), English author and social critic
- Oś, Kluczbork County, Poland
- Osiedle, a name for a housing estate in Poland
- "Os" (Fringe), an episode of the television show Fringe
O's may refer to:
- Baltimore Orioles
- Leyton Orient
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