Owyhee is an older English spelling of Hawaiʻi, used in the late 18th and early 19th centuries. It is found in the names of certain locations in the American Pacific Northwest, which were explored and mapped by expeditions whose members included native Hawaiians:
- Owyhee, Nevada, a community in north-central Nevada
- Owyhee County, Idaho, the southwesternmost county of Idaho
- Owyhee River, a river in Idaho, Nevada, and Oregon
- Owyhee Dam, a dam on the river
- Lake Owyhee, a lake in Oregon
- Owyhee Desert, a desert in Nevada