- Sports
- Tracy Austin, former World No. 1 female professional tennis player
- Pete Sampras (former tennis great)
- Lindsay Davenport, 3 time Grand Slam winner and former tennis World No. 1
- Figure skater Michelle Kwan
- Seattle Seahawks head coach Pete Carroll
- Former resident Joe Montana, of San Francisco 49ers lived in Palos Verdes Estates during the off-season.
- Pro Basketball Player Luke Walton of the Los Angeles Lakers
- Pro basketball player Pau Gasol of the Los Angeles Lakers
- Pro basketball player Sasha Vujačić of the New Jersey Nets
- Former pro basketball player Elden Campbell
- UFC Middleweight Champion Anderson Silva
- World Wrestling Entertainment (WWE) Superstar John Morrison
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- Entertainment
- George Takei famous for his work as Hikaru Sulu from Star Trek
- Former resident Chuck Norris, of Walker, Texas Ranger fame, owns several properties in the region
- Musician Gary Wright
- Musician Glenn Hughes
- Marten Andersson bass player and songwriter with the hard rock bands Lizzy Borden and Lynch Mob
- Musician James Taylor
- Juan Croucier bass player and songwriter of the bands Ratt and Dokken
- Actor Michael Dudikoff
- Actor Richard Lynch
- Author, actor and filmmaker Scott Shaw
- U.S. National Dancesport Champions (Professional Standard) and So You Think You Can Dance choreographers Heather Smith and Victor Veyrasset
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- Other
- Frank A. Vanderlip the Father of Palos Verdes.
- The Scharffenberger family of Scharffen Berger Chocolates and Scharffenberger Cellars Winery.
- Christopher Boyce and Andrew Daulton Lee, who sold U.S. secrets to the Soviets and were portrayed in the book and movieThe Falcon and the Snowman
- Billboard model Angelyne
- Billionaire John Tu
- Kamyar Kalantar-Zadeh, physician scientist and proponent of the reverse epidemiology hypothesis
- Journalist, political activist, and Holocaust denier Willis Carto
- Jack Baumann, famous for his work as a ruthless bicycle cop on TV's Pacific Blue
- Galorath Inc. CEO and President Dan Galorath
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