In Fiction
- Paracelsus is mentioned in Plate 22 of William Blake's The Marriage of Heaven and Hell.
- Arthur Schnitzler wrote a verse play Paracelsus (1899) about him
- Erwin Guido Kolbenheyer wrote a novel trilogy (Paracelsus-Tirologie, 1917-26) about him
- Paracelsus is the main character of Jorge Luis Borges's short story, The Rose of Paracelsus.
- The German drama film Paracelsus was made in 1943, directed by Georg Wilhelm Pabst. Pabst was later sharply criticised for having produced this film in Nazi Germany, subject – like all German films at the time – to the supervision of Goebbels and the considerations of Nazi propaganda.
- He is mentioned in the second chapter of Mary Wollstonecraft Shelley's Frankenstein along with Cornelius Agrippa and Albertus Magnus.
- Like Agrippa, Paracelsus is one of the 101 Famous Witches and Wizards cards that come with Chocolate Frogs in the Harry Potter universe. In the books, his statue appears in Hogwarts.
- He is mentioned in the 92nd chapter of Herman Melville's Moby Dick.
- Mark Barratt's (1991) Radio Play, "The Peacock's Tail" deals with events (some fictitious) surrounding his soujourn in Basel circa 1527. The production was first broadcast by BBC Radio 4 on 29 April 1991, with Alan Howard as Paracelsus.
- In the anime series FullMetal Alchemist, the Elric brothers' father's name is Van Hohenheim. In the remake, FullMetal Alchemist: Brotherhood, Van Hohenheim receives his name after being offered the name "Theophrastus Bombastus" by the Dwarf in the Flask and refusing it.
- Paracelsus is listed as one of the 'many Irish heroes and heroines of antiquity' in the 'Cyclops' episode of Joyce's Ulysses.
- Paracelsus figures prominently in Robertson Davies' The Cornish Trilogy first part: The Rebel Angels.
- In the game Haunting Ground, the main villain is named Aureolus.
- Paracelsus is identified as a significant influence on the unorthodox approach to healing practiced by Dr Jon Hullah in Robertson Davies novel The Cunning Man.
- In Beauty and the Beast (1987 TV series), a depraved scientist who calls himself Paracelsus is one of the principle villains of the series.
- In Nathaniel Hawthorne's The Scarlet Letter, Roger Chillingworth gives Hester Prynne a remedy that is at least as old as Paracelsus.
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