Pdr or PDR may refer to:
- Physicians' Desk Reference
- Proliferative Diabetic Retinopathy
- Paul di Resta
- Paul Ryan, U.S. politician, the nominee of the Republican Party for Vice President of the United States in the 2012 election
- Preliminary Design Review
- Pulsed Dose Rate, a form of brachytherapy
- Paintless Dent Repair
- Peripheral Distributor Road (Cardiff)—see A4232 road
- Peripheral Distributor Road (Port Talbot)—see A4241 road
- Magpul PDR (Personal Defense Rifle)
- Photodissociation regions
- Playa del Rey, Los Angeles, California
- Population and Development Review
- "Pounder" referring to Pound (mass) used as measure of caliber (artillery)
- Portia de Rossi
- Product Data Record, a concept used in Product Lifecycle Management (PLM) and Product Data Management (PDM)
- Professional Disk Recorder, a hard disk recorder from Grass Valley (company)
- Philadelphia Department of Recreation
- Purchase of development rights, otherwise known as Purchase of Agricultural Conservation Easement (PACE)—see Conservation easement
- People's Democratic Republic, e.g. Lao PDR
- Preliminary Design Review, a step in the engineering design process.