Piss(es) or Pissed may refer to:
- Urine, a sterile, liquid by-product of the body that is secreted by the kidneys and excreted through the urethra
- Urination, the ejection of urine to the outside of the body.
- Angry, pissed or pissed off-- considered mildly vulgar.
- Drunk, pissed, adj. British and Commonwealth slang, common usage but also mildly vulgar
- An alcoholic beverage of poor or inferior quality, informally.
- Piss (album), a 1993 album by Slank.
- Pissed (album), a 1994 album by Dangerous Toys.
- Pissed (2000 film), a film featuring Wendie Jo Sperber.
- Pissed (2005 film), a film featuring Marco Khan.
- Pin Index Safety System (PISS), a type of safety system