Progestin - Methods of Progestin-based Contraception

Methods of Progestin-based Contraception

It has been found that the most effective method of hormonal contraception is with a combination of estrogen and progestin. This can be done in a monophasic, biphasic, or triphasic manner. In the monophasic method, both an estrogen and a progestin are administered for 20 or 21 days and stopped for a 7- or 8-day period that includes the 5-day menstrual period. Sometimes, a 28-day regimen that includes 6 or 7 inert tablets is used. Newer biphasic and triphasic methods are now used to more closely simulate the normal menstrual cycle. Yet another method is to administer a small dose of progestin only (no estrogen) in order to decrease certain risks associated with administering estrogen, but a major side-effect is irregular bleeding usually observed during the first 18 months of such therapy.

Alternatively, it can be delivered by intra-muscular injection every several months, implant or used as intrauterine system.

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