PTH may refer to:
- Parathyroid hormone
- Pin through hole, mounting scheme used in electronics with component leads inserted through drilled holes
- Plated through hole, used in electronics to connect layers with plated through hole vias
- Polskie Towarzystwo Historyczne
- Protest the Hero, a Canadian progressive metal band from Whitby, Ontario
- GNU Portable Threads, a thread library
- The station code for Perth railway station, Scotland
- Port Huron (Amtrak station), Michigan, United States; Amtrak station code PTH
- Phenolphthalein, an indicator used in chemical reactions to indicate the presence of a base
- Parsippany-Troy Hills, a township in New Jersey, United States
- phenylthiohydantoin - a type of amino acid derivative formed by the Edman degradation
- Phantom time hypothesis, a proposed theory that a calendar change explains the lack of archaeology coinciding with the Early Middle Ages
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