Brauer Group
Further information: Brauer groupThe quaternions are "essentially" the only (non-trivial) central simple algebra (CSA) over the real numbers, in the sense that every CSA over the reals is Brauer equivalent to either the reals or the quaternions. Explicitly, the Brauer group of the reals consists of two classes, represented by the reals and the quaternions, where the Brauer group is the set of all CSAs, up to equivalence relation of one CSA being a matrix ring over another. By the Artin–Wedderburn theorem (specifically, Wedderburn's part), CSAs are all matrix algebras over a division algebra, and thus the quaternions are the only non-trivial division algebra over the reals.
CSAs – rings over a field, which are simple algebras (have no non-trivial 2-sided ideals, just as with fields) whose center is exactly the field – are a noncommutative analog of extension fields, and are more restrictive than general ring extensions. The fact that the quaternions are the only non-trivial CSA over the reals (up to equivalence) may be compared with the fact that the complex numbers are the only non-trivial field extension of the reals.
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