SCU may refer to:
- Unions
- Scottish Cyclist's Union, the sports governing body for cycling in Scotland, now known as Scottish Cycling
- Service Credit Union, New Hampshire
- Steinbach Credit Union, Canada
- Units
- Scoville Units on the Scoville scale measure the hotness or piquancy of sauces
- Serial Crimes Unit, a fictional sub-group within Condemned: Criminal Origins
- Serious Crash Unit, a New Zealand television series
- Single Compilation Unit, C/C++ specific compilation technique
- Special Commando Unit, employed by the MACV-SOG during the Vietnam War
- System Control Unit for Sega Saturn chip set
- Universities
- Santa Clara University, California, United States
- Shih Chien University, Taipei, Taiwan
- Sichuan University, Chengdu, China
- Southern Cross University, Lismore, NSW, Australia
- Southwestern Christian University, Bethany, Oklahoma
- Other
- Antonio Maceo Airport in Santiago, Cuba (IATA airport code)
- Sacra Corona Unita, a Mafia-like criminal organization from Apulia, southern Italy
- Senatus consultum ultimum, something tantamount to martial law in the times of the Roman Republic
- Service Class User - a term used in the DICOM standard
- Snoop Control Unit - A subsystem of ARM-Processors
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