Sheena is an anglicisation of Sine, the Scottish Gaelic form of the name Jane, in turn the feminine form of John. Of Hebrew origin, it means "God is gracious".
The name Sheena can refer to:
- Sheena, Queen of the Jungle, originally a comic book character
- Sheena, Queen of the Jungle, a 1950s television series
- Sheena (film), the 1984 film adaptation of the above
- Sheena (TV series), another TV series based on the above, 2000, starring Gena Lee Nolin
- Sheena Easton, a Scottish pop music vocalist
- Sheena Fujibayashi, a protagonist in Tales of Symphonia
- Strider Sheena, a character from the Strider franchise by Capcom & Moto Kikaku
- Sheena Lawrick
- Sheena Sakai, candidate on America's Next Top Model, Cycle 11 and recording artist
- Sheena, Santa Cruz, a dance-electronica band from Santa Cruz, California
- Sheena Halili, a Filipino actress