Substance may refer to:
- Chemical substance, a material with a definite chemical composition
- Drug substance
- Substance abuse, drug-related healthcare and social policy diagnosis or label
- Substance dependence, drug-related healthcare and social policy diagnosis or label
- Matter, anything that has mass and takes up space
- Substance theory, theory positing that a substance is distinct from its properties
- Substantial (rapper) a US musician
- Substance (Joy Division album), 1988
- Substance (Blank & Jones album), 2002
- Substance 1987, a New Order album
- "Substance", a song by Haste the Day from That They May Know You
- Metal Gear Solid 2: Substance, an update of the video game Metal Gear Solid 2: Sons of Liberty
- Homoousian, a Christian term meaning "same substance"
Famous quotes containing the word substance:
“But they that hold God to be [an incorporeal substance] ... do absolutely make God to be nothing at all. But how? Were they atheists? No. For though by ignorance of the consequence they said that which was equivalent to atheism, yet in their hearts they thought God a substance ... So that this atheism by consequence is a very easy thing to be fallen into, even by the most godly men of the church.”
—Thomas Hobbes (1588–1679)
“Just as a chemist “isolates” a substance from contaminations that distort his view of its nature and effects, so the work of art purifies significant appearance. It presents abstract themes in their generality, but not reduced to diagrams.”
—Rudolf Arnheim (b. 1904)
“What makes literature interesting is that it does not survive its translation. The characters in a novel are made out of the sentences. That’s what their substance is.”
—Jonathan Miller (b. 1936)