TRS may refer to:
- Theology and Religious studies, an academic discipline
- International Air Transport Association airport code for Friuli Venezia Giulia Airport (Trieste)
- Phone connector (audio), sometimes called "TRS connector" (tip/ring/sleeve), also known as the jack plug
- Teachers' Retirement System of the State of Illinois
- Teacher Retirement System of Texas
- Technical Report Series, i.e. the regulations by the World Health Organization
- Telecommunications Relay Service, also known as Telephone Relay Service
- Tandy/RadioShack
- ThalesRaytheonSystems, a manufacturer of radar and communications gear
- Three Rivers Stadium, a 1970 former stadium in Pittsburgh, Pennsylvania
- The Rocket Summer (born 1982), American indie, soul, power pop, one-man band from the Dallas/Ft. Worth, Texas area
- The Rolling Stones, an English rock band, formed in 1962
- Tuyul Rugby Sevens, an Asian-Pacific rugby union competitions
- The Red Shore, an Australian Death Metal band, formed in 2004
- Trunked radio system
- True Symphonic Rockestra
- Tough Rubber Sheath
- Term Rewriting System
- Telangana Rashtra Samithi, a political party in the Indian state of Andhra Pradesh
- Total return swap
- Total revenue share
- Trainz Railroad Simulator
- Tropical Revolving Storm
- Ticketing and Reservation System
- AirTran Airways, a low cost airline based in Orlando, Florida
- The Totally Rad Show, a weekly video podcast distributed by Revision3, hosted by Alex Albrecht, Dan Trachtenberg, and Jeff Cannata
- Timing Reference Signal, a timing signal used in Serial digital interface video transmission
- In economics, the Technical Rate of Substitution