Tuscaloosa is the name of two places in the United States of America:
- Tuscaloosa, Alabama
- Tuscaloosa County, Alabama
There is also:
- USS Tuscaloosa (CA-37), U.S. Navy New Orleans-class heavy cruiser
- USS Tuscaloosa (LST-1187), U.S. Navy Newport-class of tank landing ships (LST)
- Tuscaloosa seamount is the name given to a portion of the Nuuanu slide, a large landslide from what used to be part of Oahu, Hawaii that now lies in the Pacific Ocean north of Molokai.,
Persons:
- Chief Tuskaloosa, a Native American leader